Selasa, 30 Agustus 2011

Lupus Rash as a Common Sign of Autoimmune Disease


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Lupus generates a wide range of symptoms and many people with the disease expertise them at different intensities. Lupus entails abnormal activity of the immune system. The dysfunctional immune technique produces antibodies that turn against wholesome body cells and tissues (antinuclear antibodies). Some antibodies produced by the dysfunctional immune program can even alter the body's genetic material (anti-DNA antibodies). The abnormal activity of the immune program can lead to the occurrence of many different internal disorders (heart illness, pulmonary disease, kidney illness), disorders of the musculoskeletal method (arthritis, osteoporosis), disorders of the nervous technique (brain disease) and skin diseases (lupus rash, erythematous lesions).

In spite of the truth that patients with the autoimmune disease commonly have numerous symptoms, rash is a common sign of lupus. Lupus rash is characteristic to both systemic and discoid forms of the illness and it is in most cases the very first symptom to appear. Lupus is a chronic disease and its generated symptoms reoccur on a common time basis. Even though other symptoms might possibly come and go, lupus rash is particularly persistent and challenging to overcome.

Lupus rash frequently occurs on the body regions that are exposed to sunlight: scalp, face, neck and shoulders. Yet, the rash can also occur in other areas of the body (chest, back, palms and feet), in quite a few circumstances accompanied by skin lesions. When it occurs on the face, lupus rash has a reddish, burn-like aspect. Sometimes the rash can even have an effect on the moist tissues around the mouth and the nose. In the systemic form of the disease, lupus rash does not generally involve skin scarring and it can ameliorate with medical therapy. Lupus rash tends to aggravate if the affected skin is exposed to the sun for long periods of time.

In the discoid form of lupus, the rash occurs in several regions of the body and it affects bigger patches of skin. Discoid lupus rash entails hyperpigmentation of the skin, exfoliation and the formation of crust. The skin lesions characteristic to discoid lupus erythematosus can have an effect on deeper layers of skin and they generally heal with scarring. When it occurs on the scalp, discoid lupus rash can involve temporary or permanent hair loss (alopecia). If the rash is accompanied by intense scaling, papules and crust, the skin could possibly heal with pronounced scarring.

Subacute cutaneous lupus rash commonly occurs in the body areas that are exposed to the sun. The rash increases in size and it forms circular, scaly patches. This type of lupus rash does not involve scarring, but it usually heals with hypo-pigmentation of the skin. Subacute cutaneous lupus rash can occur in both systemic and discoid forms of the disease and it usually fades in the periods of remission. Despite the fact that it can't be entirely overcome, this symptom can also be controlled by means of the means of medical treatments. When you have lupus rash, it is really necessary to steer clear of exposing the affected skin to sunlight. Also, you should really avoid exposing the skin to irritants and chemicals, as they can seriously aggravate the rash.

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